Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CRB2 (crumbs cell polarity complex component 2) Homo sapiens
Analyze
Symbol: CRB2
Name: crumbs cell polarity complex component 2
Description: Exhibits aspartic-type endopeptidase inhibitor activity. Involved in negative regulation of endopeptidase activity. Localizes to the protein-containing complex. Implicated in focal segmental glomerulosclerosis 9.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: crumbs 2, cell polarity complex component; crumbs family member 2; crumbs homolog 2; crumbs-like protein 2; FLJ16786; FLJ38464; FSGS9; RP11-230L22.2; VMCKD
Orthologs:
Mus musculus (house mouse) : Crb2 (crumbs family member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Crb2 (crumbs cell polarity complex component 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crb2 (crumbs cell polarity complex component 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CRB2 (crumbs cell polarity complex component 2)
Canis lupus familiaris (dog) : CRB2 (crumbs cell polarity complex component 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crb2 (crumbs cell polarity complex component 2)
Sus scrofa (pig) : CRB2 (crumbs cell polarity complex component 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389123,354,065 - 123,380,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379126,118,448 - 126,141,034 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369125,158,269 - 125,180,853 (+)NCBINCBI36hg18NCBI36
Build 349123,198,002 - 123,215,932NCBI
Celera996,766,676 - 96,789,262 (+)NCBI
Cytogenetic Map9q33.3NCBI
HuRef995,733,274 - 95,755,982 (+)NCBIHuRef
CHM1_19126,267,135 - 126,291,277 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CRB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347869
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.