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Gene: SOX3 (SRY-box transcription factor 3) Homo sapiens
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Symbol: SOX3
Name: SRY-box transcription factor 3
Description: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked cognitive disability with growth hormone deficiency. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GHDX; MRGH; panhypopituitarism; PHP; PHPX; SOXB; SRY (sex determining region Y)-box 3; SRY box 3; SRY-box 3; transcription factor SOX-3
Orthologs:
Mus musculus (house mouse) : Sox3 (SRY (sex determining region Y)-box 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sox3 (SRY-box transcription factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox3 (SRY-box transcription factor 3)
Canis lupus familiaris (dog) : SOX3 (SRY-box transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox3 (SRY-box transcription factor 3)
Sus scrofa (pig) : SOX3 (SRY-box transcription factor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X140,502,987 - 140,505,060 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X139,585,152 - 139,587,225 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X139,412,818 - 139,414,891 (-)NCBINCBI36hg18NCBI36
Build 34X139,310,671 - 139,312,745NCBI
CeleraX139,957,265 - 139,959,338 (-)NCBI
Cytogenetic MapXq27.1NCBI
HuRefX128,852,437 - 128,854,510 (-)NCBIHuRef
CHM1_1X139,496,277 - 139,498,350 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SOX3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347884
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.