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Gene: HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) Homo sapiens
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Symbol: HSD3B1
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Description: Predicted to have 3-beta-hydroxy-delta5-steroid dehydrogenase activity and steroid delta-isomerase activity. Predicted to be involved in several processes, including C21-steroid hormone metabolic process; hippocampus development; and response to corticosterone. Localizes to several cellular components, including intercellular bridge; mitochondrial envelope; and nucleolus. Implicated in hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; 3BETAHSD; delta-5-3-ketosteroid isomerase; dihydrotestosterone oxidoreductase; HSD3B; HSDB3; HSDB3A; hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1; I; progesterone reductase; SDR11E1; short chain dehydrogenase/reductase family 11E, member 1; steroid Delta-isomerase; trophoblast antigen FDO161G
Orthologs:
Related Pseudogenes: HSD3BP1   HSD3BP3   HSD3BP4   HSD3BP5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1119,507,198 - 119,515,054 (+)EnsemblGRCh38hg38GRCh38
GRCh381119,507,203 - 119,515,058 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371120,049,826 - 120,057,681 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,851,349 - 119,859,204 (+)NCBINCBI36hg18NCBI36
Build 341119,761,892 - 119,769,716NCBI
Celera1118,280,577 - 118,288,432 (+)NCBI
Cytogenetic Map1p12NCBI
HuRef1117,908,314 - 117,916,173 (+)NCBIHuRef
CHM1_11120,165,347 - 120,173,201 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HSD3B1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347893
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.