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Gene: MPP1 (membrane palmitoylated protein 1) Homo sapiens
Symbol: MPP1
Name: membrane palmitoylated protein 1
Description: This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 55 kDa erythrocyte membrane protein; AAG12; aging-associated gene 12; DXS552; DXS552E; EMP55; erythrocyte membrane protein p55; membrane protein, palmitoylated 1; membrane protein, palmitoylated 1, 55kDa; migration-related gene 1; MRG1; p55; palmitoylated erythrocyte membrane protein; PEMP
Mus musculus (house mouse) : Mpp1 (membrane protein, palmitoylated)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mpp1 (membrane palmitoylated protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpp1 (membrane palmitoylated protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MPP1 (membrane palmitoylated protein 1)
Canis lupus familiaris (dog) : MPP1 (membrane palmitoylated protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpp1 (membrane palmitoylated protein 1)
Sus scrofa (pig) : MPP1 (membrane palmitoylated protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X154,778,684 - 154,805,527 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X154,006,959 - 154,033,802 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,660,162 - 153,686,957 (-)NCBINCBI36hg18NCBI36
Build 34X153,570,671 - 153,597,467NCBI
CeleraX154,165,522 - 154,192,359 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,550,319 - 142,577,036 (-)NCBIHuRef
CHM1_1X153,918,634 - 153,945,496 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MPP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347904
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.