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Gene: KPNA1 (karyopherin subunit alpha 1) Homo sapiens
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Symbol: KPNA1
Name: karyopherin subunit alpha 1
Description: Predicted to have nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus and postsynapse to nucleus signaling pathway. Localizes to the cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: importin alpha 5; importin subunit alpha-1; importin subunit alpha-5; importin-alpha-S1; IPOA5; karyopherin alpha 1 (importin alpha 5); karyopherin subunit alpha-1; NPI-1; nucleoprotein interactor 1; RAG cohort protein 2; RCH2; recombination activating gene cohort 2; SRP1; SRP1-beta
Orthologs:
Mus musculus (house mouse) : Kpna1 (karyopherin (importin) alpha 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kpna1 (karyopherin subunit alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kpna1 (karyopherin subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : KPNA1 (karyopherin subunit alpha 1)
Canis lupus familiaris (dog) : KPNA1 (karyopherin subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kpna1 (karyopherin subunit alpha 1)
Sus scrofa (pig) : KPNA1 (karyopherin subunit alpha 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3122,421,902 - 122,514,945 (-)Ensembl
GRCh383122,421,902 - 122,514,939 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373122,140,748 - 122,233,786 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,623,438 - 123,716,474 (-)NCBINCBI36hg18NCBI36
Build 343123,627,216 - 123,716,335NCBI
Celera3120,550,374 - 120,643,600 (-)NCBI
Cytogenetic Map3q21.1NCBI
HuRef3119,513,915 - 119,606,857 (-)NCBIHuRef
CHM1_13122,104,233 - 122,197,287 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KPNA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1347998
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.