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Gene: TRPM4 (transient receptor potential cation channel subfamily M member 4) Homo sapiens
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Symbol: TRPM4
Name: transient receptor potential cation channel subfamily M member 4
Description: Exhibits calcium activated cation channel activity; calcium ion binding activity; and identical protein binding activity. Involved in several processes, including protein homotetramerization; regulation of heart contraction; and sodium ion import across plasma membrane. Localizes to several cellular components, including Golgi apparatus; sodium channel complex; and spanning component of plasma membrane. Implicated in erythrokeratodermia variabilis and progressive familial heart block type IB.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium-activated non-selective cation channel 1; EKVP6; FLJ20041; hTRPM4; long transient receptor potential channel 4; LTrpC-4; LTrpC4; melastatin-4; PFHB1B; transient receptor potential cation channel, subfamily M, member 4; TRPM4B
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1949,157,741 - 49,211,836 (+)EnsemblGRCh38hg38GRCh38
GRCh381949,157,792 - 49,211,841 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371949,661,016 - 49,715,098 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,352,864 - 54,406,905 (+)NCBINCBI36hg18NCBI36
Build 341954,352,863 - 54,406,903NCBI
Celera1946,527,963 - 46,581,978 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,037,071 - 46,092,109 (+)NCBIHuRef
CHM1_11949,662,655 - 49,716,555 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Genomics

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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TRPM4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348019
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.