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Gene: RFC2 (replication factor C subunit 2) Homo sapiens
Symbol: RFC2
Name: replication factor C subunit 2
Description: Contributes to DNA clamp loader activity and single-stranded DNA helicase activity. Involved in positive regulation of DNA-directed DNA polymerase activity. Localizes to the Ctf18 RFC-like complex and DNA replication factor C complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A1; A1 40 kDa subunit; activator 1 40 kDa subunit; activator 1 subunit 2; MGC3665; replication factor C (activator 1) 2, 40kDa; replication factor C 2; RF-C 40 kDa subunit; RFC40
Mus musculus (house mouse) : Rfc2 (replication factor C (activator 1) 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rfc2 (replication factor C subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfc2 (replication factor C subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RFC2 (replication factor C subunit 2)
Canis lupus familiaris (dog) : RFC2 (replication factor C subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfc2 (replication factor C subunit 2)
Sus scrofa (pig) : RFC2 (replication factor C subunit 2)
Chlorocebus sabaeus (green monkey) : RFC2 (replication factor C subunit 2)
Heterocephalus glaber (naked mole-rat) : Rfc2 (replication factor C subunit 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl774,231,499 - 74,254,458 (-)Ensembl
GRCh38774,231,502 - 74,254,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,645,832 - 73,668,788 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,283,768 - 73,306,674 (-)NCBINCBI36hg18NCBI36
Build 34773,090,484 - 73,113,389NCBI
Celera769,125,398 - 69,148,304 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef769,527,267 - 69,550,345 (-)NCBIHuRef
CHM1_1773,790,894 - 73,813,879 (-)NCBICHM1_1
CRA_TCAGchr7v2772,978,904 - 73,001,860 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RFC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348076
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.