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Gene: IFIT5 (interferon induced protein with tetratricopeptide repeats 5) Homo sapiens
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Symbol: IFIT5
Name: interferon induced protein with tetratricopeptide repeats 5
Description: Exhibits nucleic acid binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and positive regulation of I-kappaB kinase/NF-kappaB signaling. Localizes to the actin cytoskeleton; apical part of cell; and ruffle membrane. Colocalizes with the IkappaB kinase complex; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ53857; FLJ92678; IFIT-5; interferon-induced 58 kDa protein; interferon-induced protein with tetratricopeptide repeats 5; ISG58; P58; retinoic acid- and interferon-inducible 58 kDa protein; retinoic acid- and interferon-inducible protein (58kD); RI58
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1089,414,568 - 89,420,997 (+)EnsemblGRCh38hg38GRCh38
GRCh381089,414,568 - 89,420,997 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371091,174,031 - 91,180,759 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361091,164,419 - 91,170,733 (+)NCBINCBI36hg18NCBI36
Build 341091,164,418 - 91,170,733NCBI
Celera1084,921,138 - 84,927,568 (+)NCBI
Cytogenetic Map10q23.31NCBI
HuRef1084,808,501 - 84,814,936 (+)NCBIHuRef
CHM1_11091,456,350 - 91,462,775 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IFIT5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348146
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.