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Gene: PARP10 (poly(ADP-ribose) polymerase family member 10) Homo sapiens
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Symbol: PARP10
Name: poly(ADP-ribose) polymerase family member 10
Description: Exhibits K63-linked polyubiquitin modification-dependent protein binding activity; NAD+ ADP-ribosyltransferase activity; and protein ADP-ribosylase activity. Involved in several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of macromolecule metabolic process; and protein ADP-ribosylation. Localizes to Golgi apparatus; cytosol; and nucleolus.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADP-ribosyltransferase diphtheria toxin-like 10; ARTD10; FLJ14464; PARP-10; poly (ADP-ribose) polymerase family, member 10; poly [ADP-ribose] polymerase 10
Orthologs:
Mus musculus (house mouse) : Parp10 (poly (ADP-ribose) polymerase family, member 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Parp10 (poly (ADP-ribose) polymerase family, member 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Parp10 (poly(ADP-ribose) polymerase family member 10)
Pan paniscus (bonobo/pygmy chimpanzee) : PARP10 (poly(ADP-ribose) polymerase family member 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Parp10 (poly(ADP-ribose) polymerase family member 10)
Sus scrofa (pig) : PARP10 (poly(ADP-ribose) polymerase family member 10)
Chlorocebus sabaeus (African green monkey) : PARP10 (poly(ADP-ribose) polymerase family member 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8143,977,153 - 144,012,772 (-)EnsemblGRCh38hg38GRCh38
GRCh388143,977,158 - 143,986,460 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378145,051,320 - 145,060,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,123,308 - 145,132,623 (-)NCBINCBI36hg18NCBI36
Build 348145,123,315 - 145,132,583NCBI
Celera8141,366,147 - 141,374,558 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,305,644 - 140,317,215 (-)NCBIHuRef
CHM1_18145,091,438 - 145,100,745 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PARP10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348193
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.