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Gene: SMOC1 (SPARC related modular calcium binding 1) Homo sapiens
Symbol: SMOC1
Name: SPARC related modular calcium binding 1
Description: Predicted to have calcium ion binding activity and extracellular matrix binding activity. Involved in eye development; limb development; and regulation of osteoblast differentiation. Predicted to localize to the basement membrane. Implicated in microphthalmia with limb anomalies.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: OAS; secreted modular calcium-binding protein 1; SMOC-1; SPARC-related modular calcium-binding protein 1
Mus musculus (house mouse) : Smoc1 (SPARC related modular calcium binding 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Smoc1 (SPARC related modular calcium binding 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smoc1 (SPARC related modular calcium binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SMOC1 (SPARC related modular calcium binding 1)
Canis lupus familiaris (dog) : SMOC1 (SPARC related modular calcium binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smoc1 (SPARC related modular calcium binding 1)
Sus scrofa (pig) : SMOC1 (SPARC related modular calcium binding 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381469,879,388 - 70,032,366 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371470,346,105 - 70,499,083 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361469,415,896 - 69,568,836 (+)NCBINCBI36hg18NCBI36
Build 341469,415,895 - 69,567,836NCBI
Celera1450,410,240 - 50,563,191 (+)NCBI
Cytogenetic Map14q24.2NCBI
HuRef1450,514,680 - 50,667,182 (+)NCBIHuRef
CHM1_11470,284,243 - 70,437,101 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SMOC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348217
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.