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Gene: PADI2 (peptidyl arginine deiminase 2) Homo sapiens
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Symbol: PADI2
Name: peptidyl arginine deiminase 2
Description: Exhibits several functions, including estrogen receptor binding activity; protein homodimerization activity; and protein-arginine deiminase activity. Involved in several processes, including chromatin organization; intracellular estrogen receptor signaling pathway; and regulation of chromatin disassembly. Localizes to cytoplasm and transcriptionally active chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA0994; PAD-H19; PAD2; PDI2; peptidlyarginine deiminase type II; peptidyl arginine deiminase, type II; peptidylarginine deiminase II; protein arginine deiminase; protein-arginine deiminase type II; protein-arginine deiminase type-2
Orthologs:
Mus musculus (house mouse) : Padi2 (peptidyl arginine deiminase, type II)  MGI  Alliance
Rattus norvegicus (Norway rat) : Padi2 (peptidyl arginine deiminase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Padi2 (peptidyl arginine deiminase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PADI2 (peptidyl arginine deiminase 2)
Canis lupus familiaris (dog) : PADI2 (peptidyl arginine deiminase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Padi2 (peptidyl arginine deiminase 2)
Sus scrofa (pig) : PADI2 (peptidyl arginine deiminase 2)
Chlorocebus sabaeus (African green monkey) : PADI2 (peptidyl arginine deiminase 2)
Heterocephalus glaber (naked mole-rat) : Padi2 (peptidyl arginine deiminase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl117,066,761 - 17,119,451 (-)EnsemblGRCh38hg38GRCh38
GRCh38117,066,761 - 17,119,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37117,393,256 - 17,445,948 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,265,843 - 17,318,535 (-)NCBINCBI36hg18NCBI36
Build 34117,140,558 - 17,191,236NCBI
Celera115,715,602 - 15,768,303 (-)NCBI
Cytogenetic Map1p36.13NCBI
HuRef115,637,268 - 15,689,337 (-)NCBIHuRef
CHM1_1117,501,602 - 17,554,329 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PADI2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348232
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-04-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.