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Gene: INPP5D (inositol polyphosphate-5-phosphatase D) Homo sapiens
Symbol: INPP5D
Name: inositol polyphosphate-5-phosphatase D
Description: Predicted to have phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; inositol phosphate metabolic process; and phosphatidylinositol biosynthetic process. Localizes to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hp51CN; inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145kD; inositol polyphosphate-5-phosphatase, 145kDa; MGC104855; MGC142140; MGC142142; p150Ship; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol 4,5-bisphosphate 5-phosphatase; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; SH2 containing inositol phosphatase, isoform b; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol-5'-phosphatase 1; SHIP; SHIP-1; SHIP1; signaling inositol polyphosphate 5 phosphatase SIP-145; signaling inositol polyphosphate phosphatase SHIP II; SIP-145
Mus musculus (house mouse) : Inpp5d (inositol polyphosphate-5-phosphatase D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Inpp5d (inositol polyphosphate-5-phosphatase D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5D (inositol polyphosphate-5-phosphatase D)
Canis lupus familiaris (dog) : INPP5D (inositol polyphosphate-5-phosphatase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Sus scrofa (pig) : INPP5D (inositol polyphosphate-5-phosphatase D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2233,059,967 - 233,207,903 (+)Ensembl
GRCh382233,060,342 - 233,207,903 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372234,054,795 - 234,116,549 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh372233,925,036 - 233,995,881 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,633,280 - 233,703,602 (+)NCBINCBI36hg18NCBI36
Build 362233,734,415 - 233,781,288 (+)NCBINCBI36hg18NCBI36
Build 342233,851,680 - 233,898,543NCBI
Celera2227,689,229 - 227,838,082 (+)NCBI
Cytogenetic Map2q37.1NCBI
HuRef2225,771,888 - 225,851,574 (+)NCBIHuRef
HuRef2225,855,510 - 225,917,438 (+)NCBIHuRef
CHM1_12233,930,442 - 234,122,681 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on INPP5D
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348251
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.