Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: XAGE3 (X antigen family member 3) Homo sapiens
Analyze
Symbol: XAGE3
Name: X antigen family member 3
Description: This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 12.3; cancer/testis antigen family 12, member 3a; cancer/testis antigen family 12, member 3b; CT12.3; CT12.3a; CT12.3b; G antigen family D member 4; G antigen, family D, 4; GAGED4; MGC71925; PLAC6; placenta-specific 6; placenta-specific gene 6 protein; pp9012; X antigen family, member 3; XAGE-3
Orthologs:
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC106145437 (uncharacterized LOC106145437)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X52,862,528 - 52,868,140 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X52,891,557 - 52,897,119 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X52,908,282 - 52,913,824 (-)NCBINCBI36hg18NCBI36
Build 34X52,774,578 - 52,780,120NCBI
CeleraX56,714,096 - 56,719,656 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX49,956,402 - 49,962,124 (-)NCBIHuRef
CHM1_1X52,881,677 - 52,887,239 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on XAGE3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348257
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.