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Gene: PLEKHA8 (pleckstrin homology domain containing A8) Homo sapiens
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Symbol: PLEKHA8
Name: pleckstrin homology domain containing A8
Description: Exhibits several functions, including ceramide binding activity; glycolipid transfer activity; and phosphatidylinositol-4-phosphate binding activity. Involved in ER to Golgi ceramide transport. Localizes to the nucleoplasm and trans-Golgi network; INTERACTS WITH 2-hydroxypropanoic acid; arsane; arsenic atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp313M1034; DKFZp686J09164; FAPP-2; FAPP2; hFAPP2; MGC3358; PH domain-containing family A member 8; phosphatidylinositol 4-phosphate adaptor protein-2; phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; phosphoinositol 4-phosphate adaptor protein-2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; pleckstrin homology domain-containing family A member 8; serologically defined breast cancer antigen NY-BR-86
Orthologs:
Related Pseudogenes: PLEKHA8P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,028,361 - 30,130,483 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37730,067,977 - 30,157,961 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,034,813 - 30,096,885 (+)NCBINCBI36hg18NCBI36
Build 34729,841,527 - 29,903,597NCBI
Celera730,057,679 - 30,119,744 (+)NCBI
Cytogenetic Map7p14.3NCBI
HuRef729,949,816 - 30,040,209 (+)NCBIHuRef
CHM1_1730,068,087 - 30,158,038 (+)NCBICHM1_1
CRA_TCAGchr7v2730,117,806 - 30,207,752 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLEKHA8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348276
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.