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Gene: PDE8B (phosphodiesterase 8B) Homo sapiens
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Symbol: PDE8B
Name: phosphodiesterase 8B
Description: Exhibits 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to the cytosol. Implicated in primary pigmented nodular adrenocortical disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3',5' cyclic nucleotide phosphodiesterase 8B; ADSD; cell proliferation-inducing gene 22 protein; FLJ11212; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; hsPDE8B; PPNAD3
Orthologs:
Mus musculus (house mouse) : Pde8b (phosphodiesterase 8B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde8b (phosphodiesterase 8B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde8b (phosphodiesterase 8B)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE8B (phosphodiesterase 8B)
Canis lupus familiaris (dog) : PDE8B (phosphodiesterase 8B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde8b (phosphodiesterase 8B)
Sus scrofa (pig) : PDE8B (phosphodiesterase 8B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38577,180,252 - 77,429,807 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37576,476,082 - 76,724,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36576,542,462 - 76,758,999 (+)NCBINCBI36hg18NCBI36
Build 34576,542,461 - 76,758,982NCBI
Celera572,400,947 - 72,618,614 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef571,713,174 - 71,930,868 (+)NCBIHuRef
CHM1_1575,940,448 - 76,157,815 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PDE8B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348334
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.