Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) Homo sapiens
Analyze
Symbol: SMARCA2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Description: Exhibits transcription coactivator activity and transcription regulatory region DNA binding activity. Involved in negative regulation of cell growth; negative regulation of cell population proliferation; and regulation of transcription, DNA-templated. Localizes to the SWI/SNF complex; intermediate filament cytoskeleton; and nucleoplasm. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent helicase SMARCA2; BAF190; BAF190B; brahma homolog; BRG1-associated factor 190B; BRM; FLJ36757; global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; NCBRS; probable global transcription activator SNF2L2; protein brahma homolog; SNF2; SNF2-alpha; SNF2-like 2; SNF2/SWI2-like protein 2; SNF2L2; SNF2LA; Sth1p; sucrose nonfermenting 2-like protein 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2; SWI2
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3892,015,347 - 2,193,624 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3792,015,342 - 2,193,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3692,005,342 - 2,183,624 (+)NCBINCBI36hg18NCBI36
Build 3492,005,341 - 2,183,624NCBI
Celera91,933,296 - 2,111,552 (+)NCBI
Cytogenetic Map9p24.3NCBI
HuRef91,969,240 - 2,147,484 (+)NCBIHuRef
CHM1_192,015,344 - 2,193,714 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SMARCA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348339
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.