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Gene: SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) Homo sapiens
Symbol: SMARCA2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Description: Exhibits transcription coactivator activity and transcription regulatory region DNA binding activity. Involved in negative regulation of cell growth; negative regulation of cell population proliferation; and regulation of transcription, DNA-templated. Localizes to the SWI/SNF complex; intermediate filament cytoskeleton; and nucleoplasm. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent helicase SMARCA2; BAF190; BAF190B; brahma homolog; BRG1-associated factor 190B; BRM; FLJ36757; global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; NCBRS; probable global transcription activator SNF2L2; protein brahma homolog; SNF2; SNF2-alpha; SNF2-like 2; SNF2/SWI2-like protein 2; SNF2L2; SNF2LA; Sth1p; sucrose nonfermenting 2-like protein 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2; SWI2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3892,015,347 - 2,193,624 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3792,015,342 - 2,193,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3692,005,342 - 2,183,624 (+)NCBINCBI36hg18NCBI36
Build 3492,005,341 - 2,183,624NCBI
Celera91,933,296 - 2,111,552 (+)NCBI
Cytogenetic Map9p24.3NCBI
HuRef91,969,240 - 2,147,484 (+)NCBIHuRef
CHM1_192,015,344 - 2,193,714 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SMARCA2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348339
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.