Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: DCLRE1C (DNA cross-link repair 1C) Homo sapiens
Analyze
Symbol: DCLRE1C
Name: DNA cross-link repair 1C
CRRD ID: 1348428
Description: Exhibits 5'-3' exonuclease activity and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process. Localizes to Golgi apparatus; nonhomologous end joining complex; and nucleoplasm. Implicated in Omenn syndrome; common variable immunodeficiency; severe combined immunodeficiency; and severe combined immunodeficiency with sensitivity to ionizing radiation.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A-SCID; DCLREC1C; DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1C protein; FLJ11360; FLJ36438; hSNM1C; protein artemis; PSO2 homolog; RS-SCID; SCIDA; severe combined immunodeficiency, type a (Athabascan); SNM1 homolog C; SNM1-like protein; SNM1C
Orthologs:
Mus musculus (house mouse) : Dclre1c (DNA cross-link repair 1C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dclre1c (DNA cross-link repair 1C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dclre1c (DNA cross-link repair 1C)
Pan paniscus (bonobo/pygmy chimpanzee) : DCLRE1C (DNA cross-link repair 1C)
Canis lupus familiaris (dog) : DCLRE1C (DNA cross-link repair 1C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dclre1c (DNA cross-link repair 1C)
Sus scrofa (pig) : DCLRE1C (DNA cross-link repair 1C)
Chlorocebus sabaeus (African green monkey) : DCLRE1C (DNA cross-link repair 1C)
Heterocephalus glaber (naked mole-rat) : Dclre1c (DNA cross-link repair 1C)
more info ...
Related Pseudogenes: DCLRE1CP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1014,897,359 - 14,954,432 (-)EnsemblGRCh38hg38GRCh38
GRCh381014,897,359 - 14,954,432 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371014,948,870 - 14,996,106 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,988,876 - 15,036,100 (-)NCBINCBI36hg18NCBI36
Build 341014,989,883 - 15,036,100NCBI
Celera1014,876,909 - 14,924,986 (-)NCBI
Cytogenetic Map10p13NCBI
HuRef1014,859,351 - 14,906,283 (-)NCBIHuRef
CHM1_11014,946,730 - 14,996,567 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DCLRE1C
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348428
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.