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Gene: AP1S2 (adaptor related protein complex 1 subunit sigma 2) Homo sapiens
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Symbol: AP1S2
Name: adaptor related protein complex 1 subunit sigma 2
Description: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adapter-related protein complex 1 sigma-1B subunit; adapter-related protein complex 1 subunit sigma-1B; adaptor protein complex AP-1 sigma-1B subunit; adaptor protein complex AP-1 subunit sigma-1B; adaptor related protein complex 1 sigma 2 subunit; adaptor-related protein complex 1 sigma 2 subunit; adaptor-related protein complex 1 subunit sigma-1B; adaptor-related protein complex 1, sigma 2 subunit; AP-1 complex subunit sigma-2; clathrin adaptor complex AP1 sigma 1B subunit; clathrin assembly protein complex 1 sigma-1B small chain; clathrin-associated/assembly/adaptor protein small 1-like; DC22; golgi adaptor HA1/AP1 adaptin sigma 1B subunit; golgi adaptor HA1/AP1 adaptin sigma-1B subunit; mental retardation, X-linked 59; mental retardation, X-linked, syndromic 5; MGC:1902; MRX59; MRXS21; MRXS5; MRXSF; Pettigrew X-linked mental retardation syndrome; PGS; sigma 1B subunit of AP-1 clathrin; sigma-adaptin 1B; SIGMA1B; sigma1B-adaptin
Orthologs:
Related Pseudogenes: AP1S2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X15,825,806 - 15,855,014 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,843,929 - 15,873,137 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,753,850 - 15,783,021 (-)NCBINCBI36hg18NCBI36
Build 34X15,603,585 - 15,632,757NCBI
CeleraX19,961,411 - 19,990,500 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,597,581 - 13,626,785 (-)NCBIHuRef
CHM1_1X15,874,896 - 15,904,078 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AP1S2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348501
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.