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Gene: FOXP3 (forkhead box P3) Homo sapiens
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Symbol: FOXP3
Name: forkhead box P3
Description: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AIID; DIETER; forkhead box protein P3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; scurfin; XPID
Orthologs:
Mus musculus (house mouse) : Foxp3 (forkhead box P3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Foxp3 (forkhead box P3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxp3 (forkhead box P3)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXP3 (forkhead box P3)
Canis lupus familiaris (dog) : FOXP3 (forkhead box P3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxp3 (forkhead box P3)
Sus scrofa (pig) : FOXP3 (forkhead box P3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,250,436 - 49,264,932 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,106,897 - 49,122,200 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,994,354 - 49,008,232 (-)NCBINCBI36hg18NCBI36
Build 34X48,863,780 - 48,877,659NCBI
CeleraX52,543,105 - 52,557,472 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,763,332 - 46,777,541 (-)NCBIHuRef
CHM1_1X49,139,199 - 49,153,588 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FOXP3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348507
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.