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Gene: PABPC5 (poly(A) binding protein cytoplasmic 5) Homo sapiens
Symbol: PABPC5
Name: poly(A) binding protein cytoplasmic 5
Description: This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ51677; PABP5; poly(A) binding protein, cytoplasmic 5; polyadenylate-binding protein 5
Mus musculus (house mouse) : Pabpc5 (poly(A) binding protein, cytoplasmic 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pabpc5 (poly A binding protein, cytoplasmic 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pabpc5 (poly(A) binding protein cytoplasmic 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PABPC5 (poly(A) binding protein cytoplasmic 5)
Canis lupus familiaris (dog) : PABPC5 (poly(A) binding protein cytoplasmic 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pabpc5 (poly(A) binding protein cytoplasmic 5)
Sus scrofa (pig) : LOC100518351 (polyadenylate-binding protein 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X91,434,598 - 91,438,584 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X90,689,597 - 90,693,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X90,576,253 - 90,580,239 (+)NCBINCBI36hg18NCBI36
Build 34X90,495,741 - 90,499,727NCBI
CeleraX91,182,192 - 91,186,295 (+)NCBI
Cytogenetic MapXq21.31NCBI
HuRefY2,355,075 - 2,359,061 (+)NCBIHuRef
CHM1_1X90,582,274 - 90,586,260 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PABPC5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348533
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.