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Gene: CDK8 (cyclin dependent kinase 8) Homo sapiens
Symbol: CDK8
Name: cyclin dependent kinase 8
Description: Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Localizes to the mediator complex and nucleolus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDK8 protein kinase; cell division protein kinase 8; cyclin-dependent kinase 8; K35; mediator complex subunit CDK8; mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; protein kinase K35
Mus musculus (house mouse) : Cdk8 (cyclin-dependent kinase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk8 (cyclin-dependent kinase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk8 (cyclin dependent kinase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK8 (cyclin dependent kinase 8)
Canis lupus familiaris (dog) : CDK8 (cyclin dependent kinase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk8 (cyclin dependent kinase 8)
Sus scrofa (pig) : CDK8 (cyclin dependent kinase 8)
more info ...
Related Pseudogenes: CDK8P1   CDK8P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381326,254,125 - 26,405,238 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371326,828,262 - 26,979,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361325,726,756 - 25,876,569 (+)NCBINCBI36hg18NCBI36
Build 341325,726,755 - 25,876,569NCBI
Celera137,896,857 - 8,046,682 (+)NCBI
Cytogenetic Map13q12.13NCBI
HuRef137,646,374 - 7,796,038 (+)NCBIHuRef
CHM1_11326,796,281 - 26,947,427 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CDK8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348539
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.