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Gene: CDK8 (cyclin dependent kinase 8) Homo sapiens
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Symbol: CDK8
Name: cyclin dependent kinase 8
Description: Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Localizes to the mediator complex and nucleolus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDK8 protein kinase; cell division protein kinase 8; cyclin-dependent kinase 8; K35; mediator complex subunit CDK8; mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; protein kinase K35
Orthologs:
Mus musculus (house mouse) : Cdk8 (cyclin-dependent kinase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk8 (cyclin-dependent kinase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk8 (cyclin dependent kinase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK8 (cyclin dependent kinase 8)
Canis lupus familiaris (dog) : CDK8 (cyclin dependent kinase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk8 (cyclin dependent kinase 8)
Sus scrofa (pig) : CDK8 (cyclin dependent kinase 8)
more info ...
Related Pseudogenes: CDK8P1   CDK8P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381326,254,125 - 26,405,238 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371326,828,262 - 26,979,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361325,726,756 - 25,876,569 (+)NCBINCBI36hg18NCBI36
Build 341325,726,755 - 25,876,569NCBI
Celera137,896,857 - 8,046,682 (+)NCBI
Cytogenetic Map13q12.13NCBI
HuRef137,646,374 - 7,796,038 (+)NCBIHuRef
CHM1_11326,796,281 - 26,947,427 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDK8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348539
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.