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Gene: H2BC11 (H2B clustered histone 11) Homo sapiens
Symbol: H2BC11
Name: H2B clustered histone 11
Description: Exhibits lipopolysaccharide binding activity. Involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; defense response to other organism; and negative regulation of tumor necrosis factor-mediated signaling pathway. Localizes to the cytosol; extracellular space; and nucleoplasm. Colocalizes with the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2B histone family, member R; H2B/r; H2BFR; H2BJ; HIST1H2BJ; histone 1, H2bj; histone cluster 1 H2B family member j; histone cluster 1, H2bj; histone H2B type 1-J; histone H2B.1; histone H2B.r
Mus musculus (house mouse) : H2bc21 (H2B clustered histone 21)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hist2h2be (histone cluster 2 H2B family member E)  Alliance
Canis lupus familiaris (dog) : H2BC11 (H2B clustered histone 11)
more info ...
Related Pseudogenes: H2BP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl627,125,897 - 27,132,750 (-)Ensembl
GRCh38627,132,316 - 27,132,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37627,093,912 - 27,100,743 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36627,208,074 - 27,208,554 (-)NCBINCBI36hg18NCBI36
Build 34627,208,073 - 27,208,554NCBI
Celera628,706,094 - 28,706,574 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef626,908,156 - 26,908,636 (-)NCBIHuRef
CHM1_1627,102,417 - 27,102,897 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2BC11
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348596
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.