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Gene: E4F1 (E4F transcription factor 1) Homo sapiens
Symbol: E4F1
Name: E4F transcription factor 1
Description: Exhibits cAMP response element binding activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of cell cycle process. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E4F; MGC99614; p120E4F; p50E4F; putative E3 ubiquitin-protein ligase E4F1; RING-type E3 ubiquitin transferase E4F1; transcription factor E4F; transcription factor E4F1
Mus musculus (house mouse) : E4f1 (E4F transcription factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : E4f1 (E4F transcription factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E4f1 (E4F transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : E4F1 (E4F transcription factor 1)
Canis lupus familiaris (dog) : E4F1 (E4F transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E4f1 (E4F transcription factor 1)
Sus scrofa (pig) : E4F1 (E4F transcription factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38162,223,488 - 2,235,742 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37162,273,490 - 2,285,743 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,213,568 - 2,225,744 (+)NCBINCBI36hg18NCBI36
Build 34162,213,589 - 2,225,743NCBI
Celera162,487,988 - 2,500,164 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef162,199,659 - 2,211,835 (+)NCBIHuRef
CHM1_1162,273,418 - 2,285,692 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on E4F1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348626
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.