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Gene: YTHDC2 (YTH domain containing 2) Homo sapiens
Symbol: YTHDC2
Name: YTH domain containing 2
CRRD ID: 1348696
Description: Exhibits ATPase activity; N6-methyladenosine-containing RNA binding activity; and RNA polymerase binding activity. Involved in positive regulation by host of viral genome replication; response to interleukin-1; and response to tumor necrosis factor. Localizes to endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3'-5' RNA helicase YTHDC2; CAHL; CsA-associated helicase-like protein; hYTHDC2; probable ATP-dependent RNA helicase YTHDC2; YTH domain-containing protein 2
Mus musculus (house mouse) : Ythdc2 (YTH domain containing 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ythdc2 (YTH domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ythdc2 (YTH domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : YTHDC2 (YTH domain containing 2)
Canis lupus familiaris (dog) : YTHDC2 (YTH domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ythdc2 (YTH domain containing 2)
Sus scrofa (pig) : YTHDC2 (YTH domain containing 2)
Chlorocebus sabaeus (African green monkey) : YTHDC2 (YTH domain containing 2)
Heterocephalus glaber (naked mole-rat) : Ythdc2 (YTH domain containing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl5113,513,694 - 113,595,285 (+)EnsemblGRCh38hg38GRCh38
GRCh385113,513,683 - 113,595,284 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375112,849,391 - 112,930,984 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365112,877,309 - 112,958,880 (+)NCBINCBI36hg18NCBI36
Build 345112,877,308 - 112,958,878NCBI
Celera5108,797,205 - 108,878,222 (+)NCBI
Cytogenetic Map5q22.2NCBI
HuRef5108,032,302 - 108,113,324 (+)NCBIHuRef
CHM1_15112,282,881 - 112,363,984 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on YTHDC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348696
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.