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Gene: MAGEA8 (MAGE family member A8) Homo sapiens
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Symbol: MAGEA8
Name: MAGE family member A8
Description: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 1.8; cancer/testis antigen family 1, member 8; CT1.8; MAGE-8 antigen; MAGE8; melanoma antigen family A, 8; melanoma antigen family A8; melanoma-associated antigen 8; MGC2182
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X149,881,141 - 149,885,835 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X149,009,941 - 149,014,609 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X148,770,654 - 148,775,266 (+)NCBINCBI36hg18NCBI36
Build 34X148,668,507 - 148,673,120NCBI
CeleraX149,293,931 - 149,298,625 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX137,914,473 - 137,916,695 (+)NCBIHuRef
CHM1_1X148,923,699 - 148,928,393 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MAGEA8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348802
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.