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Gene: GPSM1 (G protein signaling modulator 1) Homo sapiens
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Symbol: GPSM1
Name: G protein signaling modulator 1
Description: Exhibits GDP-dissociation inhibitor activity. Involved in negative regulation of GTPase activity; negative regulation of guanyl-nucleotide exchange factor activity; and positive regulation of macroautophagy. Localizes to several cellular components, including the Golgi apparatus; nucleoplasm; and plasma membrane. Colocalizes with the Golgi membrane; cell cortex; and endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1810037C22Rik; activator of G-protein signaling 3; AGS3; AGS3 homolog; DKFZp727I051; G-protein signaling modulator 1; G-protein signaling modulator 1 (AGS3-like, C. elegans); G-protein signalling modulator 1 (AGS3-like, C. elegans); G-protein-signaling modulator 1
Orthologs:
Mus musculus (house mouse) : Gpsm1 (G-protein signalling modulator 1 (AGS3-like, C. elegans))  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpsm1 (G-protein signaling modulator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpsm1 (G protein signaling modulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPSM1 (G protein signaling modulator 1)
Canis lupus familiaris (dog) : GPSM1 (G protein signaling modulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpsm1 (G protein signaling modulator 1)
Sus scrofa (pig) : GPSM1 (G protein signaling modulator 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,327,539 - 136,359,605 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379139,221,932 - 139,254,057 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,348,726 - 138,372,493 (+)NCBINCBI36hg18NCBI36
Build 349136,504,741 - 136,528,509NCBI
Celera9109,736,118 - 109,768,993 (+)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9108,681,506 - 108,713,413 (+)NCBIHuRef
CHM1_19139,370,654 - 139,402,253 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GPSM1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348855
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.