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Gene: CANT1 (calcium activated nucleotidase 1) Homo sapiens
Symbol: CANT1
Name: calcium activated nucleotidase 1
Description: Exhibits calcium ion binding activity; nucleoside-diphosphatase activity; and protein homodimerization activity. Involved in proteoglycan biosynthetic process. Localizes to the membrane. Implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apyrase homolog; Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase; DBQD; DBQD1; EDM7; micromelic dwarfism with vertebral and metaphyseal abnormalities and advanced carpotarsal ossification; putative MAPK-activating protein PM09; putative NF-kappa-B-activating protein 107; SCAN-1; SCAN1; SHAPY; soluble Ca-activated nucleotidase, isozyme 1; soluble calcium-activated nucleotidase 1; soluble calcium-activated nucleotidase SCAN-1
Mus musculus (house mouse) : Cant1 (calcium activated nucleotidase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cant1 (calcium activated nucleotidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cant1 (calcium activated nucleotidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CANT1 (calcium activated nucleotidase 1)
Canis lupus familiaris (dog) : CANT1 (calcium activated nucleotidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cant1 (calcium activated nucleotidase 1)
Sus scrofa (pig) : CANT1 (calcium activated nucleotidase 1)
Chlorocebus sabaeus (green monkey) : CANT1 (calcium activated nucleotidase 1)
Heterocephalus glaber (naked mole-rat) : Cant1 (calcium activated nucleotidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1778,991,716 - 79,009,867 (-)Ensembl
GRCh381778,991,716 - 79,009,793 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371776,987,798 - 77,005,899 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361774,499,394 - 74,517,433 (-)NCBINCBI36hg18NCBI36
Build 341774,499,393 - 74,517,433NCBI
Celera1773,585,975 - 73,604,118 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1772,408,348 - 72,414,909 (-)NCBIHuRef
CHM1_11777,051,715 - 77,069,816 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CANT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1348972
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.