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Gene: CENPX (centromere protein X) Homo sapiens
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Symbol: CENPX
Name: centromere protein X
Description: Exhibits DNA binding activity. Contributes to double-stranded DNA binding activity. Involved in replication fork processing and resolution of meiotic recombination intermediates. Localizes to the FANCM-MHF complex and Fanconi anaemia nuclear complex; INTERACTS WITH (-)-demecolcine; 2-hydroxypropanoic acid; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CENP-X; D9; FAAP10; FANCM associated histone fold protein 2; FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; MGC14480; MHF2; retinoic acid-inducible gene D9 protein homolog; stimulated by retinoic acid 13; stimulated by retinoic acid 13 homolog; stimulated by retinoic acid gene 13 protein homolog; STRA13
Orthologs:
Mus musculus (house mouse) : Cenpx (centromere protein X)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cenpx (centromere protein X)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cenpx (centromere protein X)
Pan paniscus (bonobo/pygmy chimpanzee) : CENPX (centromere protein X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cenpx (centromere protein X)
Sus scrofa (pig) : CENPX (centromere protein X)
Chlorocebus sabaeus (green monkey) : CENPX (centromere protein X)
Heterocephalus glaber (naked mole-rat) : Cenpx (centromere protein X)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1782,018,702 - 82,024,107 (-)Ensembl
GRCh381782,018,703 - 82,022,930 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,976,579 - 79,980,786 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,569,868 - 77,574,062 (-)NCBINCBI36hg18NCBI36
Build 341777,569,867 - 77,574,043NCBI
Cytogenetic Map17q25.3NCBI
HuRef1775,376,818 - 75,381,025 (-)NCBIHuRef
CHM1_11780,062,667 - 80,066,873 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CENPX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349037
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.