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Gene: MEF2C (myocyte enhancer factor 2C) Homo sapiens
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Symbol: MEF2C
Name: myocyte enhancer factor 2C
CRRD ID: 1349172
Description: Exhibits several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and protein heterodimerization activity. Involved in several processes, including negative regulation of cell migration; positive regulation of cell differentiation; and regulation of transcription by RNA polymerase II. Localizes to cytoplasm; nuclear speck; and protein-containing complex. Implicated in autosomal dominant mental retardation 20.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C5DELq14.3; DEL5q14.3; MADS box transcription enhancer factor 2, polypeptide C; myocyte-specific enhancer factor 2C
Orthologs:
Mus musculus (house mouse) : Mef2c (myocyte enhancer factor 2C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mef2c (myocyte enhancer factor 2C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2c (myocyte enhancer factor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2C (myocyte enhancer factor 2C)
Canis lupus familiaris (dog) : MEF2C (myocyte enhancer factor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2c (myocyte enhancer factor 2C)
Sus scrofa (pig) : MEF2C (myocyte enhancer factor 2C)
Chlorocebus sabaeus (African green monkey) : MEF2C (myocyte enhancer factor 2C)
Heterocephalus glaber (naked mole-rat) : Mef2c (myocyte enhancer factor 2C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl588,717,117 - 88,904,257 (-)EnsemblGRCh38hg38GRCh38
GRCh38588,717,117 - 88,904,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37588,014,058 - 88,199,922 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36588,051,922 - 88,214,780 (-)NCBINCBI36hg18NCBI36
Build 34588,051,921 - 88,214,780NCBI
Celera583,907,023 - 84,092,551 (-)NCBI
Cytogenetic Map5q14.3NCBI
HuRef583,218,989 - 83,404,187 (-)NCBIHuRef
CHM1_1587,447,103 - 87,632,656 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MEF2C
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349172
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.