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Gene: PLXNA3 (plexin A3) Homo sapiens
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Symbol: PLXNA3
Name: plexin A3
Description: This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6.3; HSSEXGENE; plexin-4; plexin-A3; PLXN3; PLXN4; semaphorin receptor SEX; SEX; Sex chromosome X transmembrane protein of HGF receptor family 3; XAP-6
Orthologs:
Mus musculus (house mouse) : Plxna3 (plexin A3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plxna3 (plexin A3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plxna3 (plexin A3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLXNA3 (plexin A3)
Canis lupus familiaris (dog) : PLXNA3 (plexin A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plxna3 (plexin A3)
Sus scrofa (pig) : PLXNA3 (plexin A3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,458,281 - 154,473,646 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,686,623 - 153,701,985 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,339,817 - 153,355,179 (+)NCBINCBI36hg18NCBI36
Build 34X153,250,326 - 153,265,688NCBI
CeleraX153,847,674 - 153,863,036 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,263,786 - 142,279,038 (+)NCBIHuRef
CHM1_1X153,598,265 - 153,613,630 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PLXNA3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349180
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.