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Gene: PLXNA3 (plexin A3) Homo sapiens
Symbol: PLXNA3
Name: plexin A3
Description: This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6.3; HSSEXGENE; plexin-4; plexin-A3; PLXN3; PLXN4; semaphorin receptor SEX; SEX; Sex chromosome X transmembrane protein of HGF receptor family 3; XAP-6
Mus musculus (house mouse) : Plxna3 (plexin A3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plxna3 (plexin A3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plxna3 (plexin A3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLXNA3 (plexin A3)
Canis lupus familiaris (dog) : PLXNA3 (plexin A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plxna3 (plexin A3)
Sus scrofa (pig) : PLXNA3 (plexin A3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X154,458,281 - 154,473,646 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,686,623 - 153,701,985 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,339,817 - 153,355,179 (+)NCBINCBI36hg18NCBI36
Build 34X153,250,326 - 153,265,688NCBI
CeleraX153,847,674 - 153,863,036 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,263,786 - 142,279,038 (+)NCBIHuRef
CHM1_1X153,598,265 - 153,613,630 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PLXNA3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349180
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.