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Gene: XRCC2 (X-ray repair cross complementing 2) Homo sapiens
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Symbol: XRCC2
Name: X-ray repair cross complementing 2
Description: Contributes to four-way junction DNA binding activity. Involved in DNA recombination; centrosome cycle; and mitotic cell cycle. Localizes to the centrosome; nucleus; and replication fork. Implicated in Fanconi anemia complementation group U and pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp781P0919; DNA repair protein XRCC2; FANCU; RAD51-like; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross-complementing protein 2; X-ray repair, complementing defective, repair in Chinese hamster
Orthologs:
Mus musculus (house mouse) : Xrcc2 (X-ray repair complementing defective repair in Chinese hamster cells 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xrcc2 (X-ray repair cross complementing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc2 (X-ray repair cross complementing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : XRCC2 (X-ray repair cross complementing 2)
Canis lupus familiaris (dog) : XRCC2 (X-ray repair cross complementing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc2 (X-ray repair cross complementing 2)
Sus scrofa (pig) : XRCC2 (X-ray repair cross complementing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387152,644,776 - 152,676,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377152,343,583 - 152,373,250 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367151,974,516 - 152,004,183 (-)NCBINCBI36hg18NCBI36
Build 347151,781,236 - 151,810,898NCBI
Celera7146,907,598 - 146,937,489 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7146,154,439 - 146,184,018 (-)NCBIHuRef
CHM1_17152,351,916 - 152,381,649 (-)NCBICHM1_1
CRA_TCAGchr7v27151,670,667 - 151,700,330 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on XRCC2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349181
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.