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Gene: XRCC2 (X-ray repair cross complementing 2) Homo sapiens
Symbol: XRCC2
Name: X-ray repair cross complementing 2
Description: Contributes to four-way junction DNA binding activity. Involved in DNA recombination; centrosome cycle; and mitotic cell cycle. Localizes to the centrosome; nucleus; and replication fork. Implicated in Fanconi anemia complementation group U and pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp781P0919; DNA repair protein XRCC2; FANCU; RAD51-like; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross-complementing protein 2; X-ray repair, complementing defective, repair in Chinese hamster
Mus musculus (house mouse) : Xrcc2 (X-ray repair complementing defective repair in Chinese hamster cells 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xrcc2 (X-ray repair cross complementing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc2 (X-ray repair cross complementing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : XRCC2 (X-ray repair cross complementing 2)
Canis lupus familiaris (dog) : XRCC2 (X-ray repair cross complementing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc2 (X-ray repair cross complementing 2)
Sus scrofa (pig) : XRCC2 (X-ray repair cross complementing 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387152,644,776 - 152,676,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377152,343,583 - 152,373,250 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367151,974,516 - 152,004,183 (-)NCBINCBI36hg18NCBI36
Build 347151,781,236 - 151,810,898NCBI
Celera7146,907,598 - 146,937,489 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7146,154,439 - 146,184,018 (-)NCBIHuRef
CHM1_17152,351,916 - 152,381,649 (-)NCBICHM1_1
CRA_TCAGchr7v27151,670,667 - 151,700,330 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on XRCC2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349181
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.