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Gene: MAGEE1 (MAGE family member E1) Homo sapiens
Symbol: MAGEE1
Name: MAGE family member E1
Description: This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to cognitive disability. [provided by RefSeq, Mar 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-dystrobrevin-associated MAGE Protein; DAMAGE; dystrobrevin-associated MAGE protein; HCA1; hepatocellular carcinoma-associated HCA1; hepatocellular carcinoma-associated protein 1; KIAA1587; MAGE-E1 antigen; melanoma antigen family E, 1; melanoma antigen family E1; melanoma-associated antigen E1
Mus musculus (house mouse) : Magee1 (melanoma antigen, family E, 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Magee1 (MAGE family member E1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Magee1 (MAGE family member E1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAGEE1 (MAGE family member E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Magee1 (MAGE family member E1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X76,427,653 - 76,431,353 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X75,648,046 - 75,651,746 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X75,564,521 - 75,568,148 (+)NCBINCBI36hg18NCBI36
Build 34X75,430,816 - 75,434,444NCBI
CeleraX75,927,786 - 75,931,486 (+)NCBI
Cytogenetic MapXq13.3NCBI
HuRefX69,280,072 - 69,283,772 (+)NCBIHuRef
CHM1_1X75,540,855 - 75,544,555 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MAGEE1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349261
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.