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Gene: ZNF81 (zinc finger protein 81) Homo sapiens
Symbol: ZNF81
Name: zinc finger protein 81
Description: This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ54B20.6; FLJ44367; HFZ20; mental retardation, X-linked 45; MRX45; zinc finger protein 81 (hfz20)
Rattus norvegicus (Norway rat) : LOC100363372 (zinc finger protein 81 (HFZ20)-like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znf81 (zinc finger protein 81)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF81 (zinc finger protein 81)
Canis lupus familiaris (dog) : ZNF81 (zinc finger protein 81)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znf81 (zinc finger protein 81)
Sus scrofa (pig) : ZNF81 (zinc finger protein 81)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X47,836,864 - 47,925,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X47,696,270 - 47,781,655 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X47,581,245 - 47,666,554 (+)NCBINCBI36hg18NCBI36
Build 34X47,452,554 - 47,537,860NCBI
CeleraX51,891,597 - 51,976,926 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX45,408,032 - 45,493,828 (+)NCBIHuRef
CHM1_1X47,727,451 - 47,812,794 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZNF81
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349324
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.