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Gene: ECE2 (endothelin converting enzyme 2) Homo sapiens
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Symbol: ECE2
Name: endothelin converting enzyme 2
Description: Exhibits metalloendopeptidase activity. Involved in peptide hormone processing. Localizes to the cytoplasmic vesicle membrane; INTERACTS WITH 17beta-estradiol; afimoxifene; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ECE-2; EEF1A lysine methyltransferase 4; EEF1AKMT4; EEF1AKMT4-ECE2; endothelin-converting enzyme 2; hypothetical protein MGC2408; KIAA0604; MGC17664; MGC2408; MGC78487
Orthologs:
Mus musculus (house mouse) : Ece2 (endothelin converting enzyme 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ece2 (endothelin-converting enzyme 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ece2 (endothelin converting enzyme 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100975702 (endothelin-converting enzyme 2)
Canis lupus familiaris (dog) : ECE2 (endothelin converting enzyme 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ece2 (endothelin converting enzyme 2)
Sus scrofa (pig) : ECE2 (endothelin converting enzyme 2)
Heterocephalus glaber (naked mole-rat) : Ece2 (endothelin converting enzyme 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3184,276,011 - 184,293,031 (+)Ensembl
GRCh383184,276,022 - 184,293,031 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373183,967,445 - 184,010,819 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,450,139 - 185,493,513 (+)NCBINCBI36hg18NCBI36
Build 343185,450,218 - 185,493,520NCBI
Celera3182,408,209 - 182,451,576 (+)NCBI
Cytogenetic Map3q27.1NCBI
HuRef3181,374,414 - 181,417,820 (+)NCBIHuRef
CHM1_13183,931,867 - 183,975,288 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ECE2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349338
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.