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Gene: IRX1 (iroquois homeobox 1) Homo sapiens
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Symbol: IRX1
Name: iroquois homeobox 1
Description: Exhibits sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeodomain protein IRXA1; iroquois homeobox protein 1; iroquois-class homeodomain protein IRX-1; IRX-5; IRXA1
Orthologs:
Mus musculus (house mouse) : Irx1 (Iroquois homeobox 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irx1 (iroquois homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irx1 (iroquois homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IRX1 (iroquois homeobox 1)
Canis lupus familiaris (dog) : IRX1 (iroquois homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irx1 (iroquois homeobox 1)
Sus scrofa (pig) : IRX1 (iroquois homeobox 1)
more info ...
Related Pseudogenes: IRX1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl53,595,832 - 3,601,403 (+)Ensembl
GRCh3853,595,832 - 3,601,403 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3753,596,168 - 3,601,517 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3653,649,168 - 3,654,517 (+)NCBINCBI36hg18NCBI36
Build 3453,649,167 - 3,654,517NCBI
Celera53,626,588 - 3,631,937 (+)NCBI
Cytogenetic Map5p15.33NCBI
HuRef53,569,035 - 3,575,436 (+)NCBIHuRef
CHM1_153,596,269 - 3,601,617 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on IRX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349465
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.