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Gene: KLHL4 (kelch like family member 4) Homo sapiens
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Symbol: KLHL4
Name: kelch like family member 4
Description: This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKELCHL; kelch-like family member 4; kelch-like protein 4; KHL4; KIAA1687
Orthologs:
Mus musculus (house mouse) : Klhl4 (kelch-like 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klhl4 (kelch-like family member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klhl4 (kelch like family member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : KLHL4 (kelch like family member 4)
Canis lupus familiaris (dog) : KLHL4 (kelch like family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klhl4 (kelch like family member 4)
Sus scrofa (pig) : KLHL4 (kelch like family member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X87,517,712 - 87,670,050 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X86,772,715 - 86,925,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X86,659,465 - 86,811,706 (+)NCBINCBI36hg18NCBI36
Build 34X86,578,961 - 86,730,741NCBI
CeleraX87,012,392 - 87,164,729 (+)NCBI
Cytogenetic MapXq21.31NCBI
HuRefX80,353,756 - 80,506,308 (+)NCBIHuRef
CHM1_1X86,665,377 - 86,817,732 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KLHL4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349490
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.