Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ANG (angiogenin) Homo sapiens
Symbol: ANG
Name: angiogenin
Description: Exhibits several functions, including actin binding activity; heparin binding activity; and protein homodimerization activity. Involved in several processes, including activation of protein kinase B activity; defense response to other organism; and positive regulation of phospholipase activity. Localizes to several cellular components, including the angiogenin-PRI complex; basement membrane; and nucleolus. Implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Biomarker of several diseases, including eosinophilic esophagitis; female reproductive organ cancer (multiple); neurodegenerative disease (multiple); rheumatoid arthritis; and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALS9; angiogenin, ribonuclease, RNase A family, 5; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5
Mus musculus (house mouse) : Ang (angiogenin, ribonuclease, RNase A family, 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ang (angiogenin)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ANG (angiogenin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ang (angiogenin)
Sus scrofa (pig) : ANG (angiogenin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381420,684,177 - 20,694,186 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371421,152,336 - 21,162,345 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,222,176 - 20,232,185 (+)NCBINCBI36hg18NCBI36
Build 341420,222,608 - 20,232,183NCBI
Celera141,013,208 - 1,023,217 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef141,273,259 - 1,283,264 (+)NCBIHuRef
CHM1_11421,154,356 - 21,164,361 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ANG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349500
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.