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Gene: ANG (angiogenin) Homo sapiens
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Symbol: ANG
Name: angiogenin
Description: Exhibits several functions, including actin binding activity; heparin binding activity; and protein homodimerization activity. Involved in several processes, including activation of protein kinase B activity; defense response to other organism; and positive regulation of phospholipase activity. Localizes to several cellular components, including the angiogenin-PRI complex; basement membrane; and nucleolus. Implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Biomarker of several diseases, including eosinophilic esophagitis; female reproductive organ cancer (multiple); neurodegenerative disease (multiple); rheumatoid arthritis; and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALS9; angiogenin, ribonuclease, RNase A family, 5; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5
Orthologs:
Mus musculus (house mouse) : Ang (angiogenin, ribonuclease, RNase A family, 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ang (angiogenin)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ANG (angiogenin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ang (angiogenin)
Sus scrofa (pig) : ANG (angiogenin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,684,177 - 20,694,186 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371421,152,336 - 21,162,345 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,222,176 - 20,232,185 (+)NCBINCBI36hg18NCBI36
Build 341420,222,608 - 20,232,183NCBI
Celera141,013,208 - 1,023,217 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef141,273,259 - 1,283,264 (+)NCBIHuRef
CHM1_11421,154,356 - 21,164,361 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ANG
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349500
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.