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Gene: DDX6 (DEAD-box helicase 6) Homo sapiens
Symbol: DDX6
Name: DEAD-box helicase 6
Description: Exhibits protein domain specific binding activity. Involved in cytoplasmic mRNA processing body assembly and viral RNA genome packaging. Localizes to several cellular components, including the RISC complex; cytoplasmic ribonucleoprotein granule; and cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD box protein 6; DEAD box-6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); FLJ36338; HLR2; IDDILF; oncogene RCK; P54; probable ATP-dependent RNA helicase DDX6; RCK
Mus musculus (house mouse) : Ddx6 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ddx6 (DEAD-box helicase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx6 (DEAD-box helicase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX6 (DEAD-box helicase 6)
Canis lupus familiaris (dog) : DDX6 (DEAD-box helicase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx6 (DEAD-box helicase 6)
Sus scrofa (pig) : DDX6 (DEAD-box helicase 6)
more info ...
Related Pseudogenes: DDX6P1   DDX6P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11118,747,763 - 118,791,164 (-)Ensembl
GRCh3811118,747,763 - 118,791,696 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,618,472 - 118,661,972 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,125,623 - 118,167,082 (-)NCBINCBI36hg18NCBI36
Build 3411118,125,622 - 118,167,082NCBI
Celera11115,780,242 - 115,819,622 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,556,823 - 114,600,235 (-)NCBIHuRef
CHM1_111118,505,094 - 118,548,632 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DDX6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349712
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.