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Gene: SERAC1 (serine active site containing 1) Homo sapiens
Symbol: SERAC1
Name: serine active site containing 1
Description: Involved in intracellular cholesterol transport and phosphatidylglycerol acyl-chain remodeling. Localizes to the endoplasmic reticulum; mitochondria-associated endoplasmic reticulum membrane; and mitochondrion. Implicated in 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ14917; FLJ30544; MEGDEL; serine active site-containing protein 1
Mus musculus (house mouse) : Serac1 (serine active site containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Serac1 (serine active site containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serac1 (serine active site containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERAC1 (serine active site containing 1)
Canis lupus familiaris (dog) : SERAC1 (serine active site containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serac1 (serine active site containing 1)
Sus scrofa (pig) : SERAC1 (serine active site containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh386158,109,515 - 158,168,270 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376158,530,536 - 158,589,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,450,535 - 158,509,257 (-)NCBINCBI36hg18NCBI36
Build 346158,500,957 - 158,559,678NCBI
Celera6159,179,384 - 159,237,341 (-)NCBI
Cytogenetic Map6q25.3NCBI
HuRef6156,002,634 - 156,060,523 (-)NCBIHuRef
CHM1_16158,792,759 - 158,851,576 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SERAC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349770
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.