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Gene: GPRASP1 (G protein-coupled receptor associated sorting protein 1) Homo sapiens
Symbol: GPRASP1
Name: G protein-coupled receptor associated sorting protein 1
Description: This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1; KIAA0443
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X102,651,366 - 102,659,083 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X101,906,294 - 101,914,011 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X101,792,950 - 101,800,667 (+)NCBINCBI36hg18NCBI36
Build 34X101,712,586 - 101,719,523NCBI
CeleraX102,344,925 - 102,352,642 (+)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX91,571,439 - 91,579,193 (+)NCBIHuRef
CHM1_1X101,798,965 - 101,806,682 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPRASP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349786
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.