Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: WDR5 (WD repeat domain 5) Homo sapiens
Symbol: WDR5
Name: WD repeat domain 5
Description: Exhibits methylated histone binding activity. Contributes to H4 histone acetyltransferase activity and histone methyltransferase activity (H3-K4 specific). Involved in histone modification. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; WD repeat-containing protein 5; WD-repeat protein 5
Mus musculus (house mouse) : Wdr5 (WD repeat domain 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr5 (WD repeat domain 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr5 (WD repeat domain 5)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR5 (WD repeat domain 5)
Canis lupus familiaris (dog) : WDR5 (WD repeat domain 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr5 (WD repeat domain 5)
Sus scrofa (pig) : WDR5 (WD repeat domain 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389134,135,382 - 134,159,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379137,000,801 - 137,025,094 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,991,031 - 136,014,915 (+)NCBINCBI36hg18NCBI36
Build 349134,034,467 - 134,053,330NCBI
Celera9107,546,368 - 107,570,384 (+)NCBI
Cytogenetic Map9q34.2NCBI
HuRef9106,494,213 - 106,518,092 (+)NCBIHuRef
CHM1_19137,147,954 - 137,171,840 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on WDR5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349800
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.