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Gene: WDR5 (WD repeat domain 5) Homo sapiens
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Symbol: WDR5
Name: WD repeat domain 5
Description: Exhibits methylated histone binding activity. Contributes to H4 histone acetyltransferase activity and histone methyltransferase activity (H3-K4 specific). Involved in histone modification. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; WD repeat-containing protein 5; WD-repeat protein 5
Orthologs:
Mus musculus (house mouse) : Wdr5 (WD repeat domain 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr5 (WD repeat domain 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr5 (WD repeat domain 5)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR5 (WD repeat domain 5)
Canis lupus familiaris (dog) : WDR5 (WD repeat domain 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr5 (WD repeat domain 5)
Sus scrofa (pig) : WDR5 (WD repeat domain 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389134,135,382 - 134,159,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379137,000,801 - 137,025,094 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,991,031 - 136,014,915 (+)NCBINCBI36hg18NCBI36
Build 349134,034,467 - 134,053,330NCBI
Celera9107,546,368 - 107,570,384 (+)NCBI
Cytogenetic Map9q34.2NCBI
HuRef9106,494,213 - 106,518,092 (+)NCBIHuRef
CHM1_19137,147,954 - 137,171,840 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on WDR5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349800
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.