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Gene: H2AB2 (H2A.B variant histone 2) Homo sapiens
Symbol: H2AB2
Name: H2A.B variant histone 2
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy. [provided by RefSeq, Oct 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A Barr body deficient; H2A Barr body-deficient; H2A histone family member B2; H2A histone family, member B2; H2A.Bbd; H2AFB2; H2AFB3; histone H2A-Bbd type 2/3
Rattus norvegicus (Norway rat) : H2afb3 (H2A histone family, member B3)  Alliance
Canis lupus familiaris (dog) : LOC612656 (histone H2A-Bbd type 2/3-like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X155,380,706 - 155,381,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X154,610,355 - 154,610,948 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X154,263,630 - 154,263,977 (+)NCBINCBI36hg18NCBI36
CeleraX154,271,944 - 154,272,291 (+)NCBI
Cytogenetic MapXq28NCBI
HuRefX143,154,484 - 143,155,077 (+)NCBIHuRef
CHM1_1X154,600,692 - 154,600,958 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H2AB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349803
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.