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Gene: ARHGAP6 (Rho GTPase activating protein 6) Homo sapiens
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Symbol: ARHGAP6
Name: Rho GTPase activating protein 6
Description: This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: rho GTPase-activating protein 6; rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1; RHOGAP6; RHOGAPX-1
Orthologs:
Mus musculus (house mouse) : Arhgap6 (Rho GTPase activating protein 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgap6 (Rho GTPase activating protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgap6 (Rho GTPase activating protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGAP6 (Rho GTPase activating protein 6)
Canis lupus familiaris (dog) : ARHGAP6 (Rho GTPase activating protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgap6 (Rho GTPase activating protein 6)
Sus scrofa (pig) : ARHGAP6 (Rho GTPase activating protein 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,137,543 - 11,665,701 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X11,155,663 - 11,683,821 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X11,065,584 - 11,593,742 (-)NCBINCBI36hg18NCBI36
Build 34X10,915,323 - 11,443,478NCBI
CeleraX15,283,114 - 15,812,107 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBIHuRef
CHM1_1X11,186,095 - 11,714,183 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ARHGAP6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349829
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.