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Gene: ARHGAP6 (Rho GTPase activating protein 6) Homo sapiens
Symbol: ARHGAP6
Name: Rho GTPase activating protein 6
Description: This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: rho GTPase-activating protein 6; rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1; RHOGAP6; RHOGAPX-1
Mus musculus (house mouse) : Arhgap6 (Rho GTPase activating protein 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgap6 (Rho GTPase activating protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgap6 (Rho GTPase activating protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGAP6 (Rho GTPase activating protein 6)
Canis lupus familiaris (dog) : ARHGAP6 (Rho GTPase activating protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgap6 (Rho GTPase activating protein 6)
Sus scrofa (pig) : ARHGAP6 (Rho GTPase activating protein 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X11,137,543 - 11,665,701 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X11,155,663 - 11,683,821 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X11,065,584 - 11,593,742 (-)NCBINCBI36hg18NCBI36
Build 34X10,915,323 - 11,443,478NCBI
CeleraX15,283,114 - 15,812,107 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX8,936,119 - 9,462,624 (-)NCBIHuRef
CHM1_1X11,186,095 - 11,714,183 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ARHGAP6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349829
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.