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Gene: KCNJ5 (potassium inwardly rectifying channel subfamily J member 5) Homo sapiens
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Symbol: KCNJ5
Name: potassium inwardly rectifying channel subfamily J member 5
Description: Exhibits voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. Contributes to inward rectifier potassium channel activity. Involved in membrane repolarization during atrial cardiac muscle cell action potential; potassium ion import across plasma membrane; and regulation of heart rate by cardiac conduction. Localizes to the voltage-gated potassium channel complex. Implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying, subfamily J, member 5) (Inward rectifier K+ channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR)...; GIRK-4; GIRK4; heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK-4; KATP-1; KATP1; KIR3.4; LQT13; potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811128,891,356 - 128,921,163 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711128,761,313 - 128,791,060 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611128,266,523 - 128,293,174 (+)NCBINCBI36hg18NCBI36
Build 3411128,266,522 - 128,293,174NCBI
Celera11125,929,625 - 125,956,261 (+)NCBI
Cytogenetic Map11q24.3NCBI
HuRef11124,711,137 - 124,737,786 (+)NCBIHuRef
CHM1_111128,647,771 - 128,674,425 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on KCNJ5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349904
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.