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Gene: MED27 (mediator complex subunit 27) Homo sapiens
Symbol: MED27
Name: mediator complex subunit 27
Description: Exhibits transcription coactivator activity. Involved in regulation of transcription by RNA polymerase II. Localizes to the cytosol; nuclear lumen; and transcription factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cofactor required for Sp1 transcriptional activation subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8 (34kD); cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; CRAP34; CRSP complex subunit 8; CRSP34; CRSP8; FLJ42238; MED3; mediator of RNA polymerase II transcription subunit 27; MGC11274; p37 TRAP/SMCC/PC2 subunit; transcriptional coactivator CRSP34; TRAP37
Mus musculus (house mouse) : Med27 (mediator complex subunit 27)  MGI  Alliance
Rattus norvegicus (Norway rat) : Med27 (mediator complex subunit 27)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MED27 (mediator complex subunit 27)
Canis lupus familiaris (dog) : MED27 (mediator complex subunit 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med27 (mediator complex subunit 27)
Sus scrofa (pig) : MED27 (mediator complex subunit 27)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389131,860,110 - 132,079,867 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379134,735,497 - 134,955,274 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369133,725,320 - 133,945,074 (-)NCBINCBI36hg18NCBI36
Build 349131,765,052 - 131,984,807NCBI
Celera9105,275,611 - 105,497,127 (-)NCBI
Cytogenetic Map9q34.13NCBI
HuRef9104,229,766 - 104,309,124 (-)NCBIHuRef
HuRef9104,352,429 - 104,449,321 (-)NCBIHuRef
CHM1_19134,885,065 - 135,104,872 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MED27
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349942
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.