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Gene: ZNRF1 (zinc and ring finger 1) Homo sapiens
Symbol: ZNRF1
Name: zinc and ring finger 1
Description: Exhibits ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein K48-linked ubiquitination. Localizes to the cytosol; endosome; and membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp434E229; E3 ubiquitin-protein ligase ZNRF1; FLJ14846; FLJ46491; MGC15430; nerve injury gene 283; nerve injury-induced gene 283 protein; NIN283; RING-type E3 ubiquitin transferase ZNRF1; zinc and ring finger 1, E3 ubiquitin protein ligase; zinc and ring finger protein 1; zinc/RING finger protein 1
Mus musculus (house mouse) : Znrf1 (zinc and ring finger 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Znrf1 (zinc and ring finger 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znrf1 (zinc and ring finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNRF1 (zinc and ring finger 1)
Canis lupus familiaris (dog) : ZNRF1 (zinc and ring finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znrf1 (zinc and ring finger 1)
Sus scrofa (pig) : ZNRF1 (zinc and ring finger 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381674,999,024 - 75,110,994 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371675,032,915 - 75,144,892 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361673,590,416 - 73,702,393 (+)NCBINCBI36hg18NCBI36
Build 341673,590,415 - 73,702,393NCBI
Celera1659,325,881 - 59,437,794 (+)NCBI
Cytogenetic Map16q23.1NCBI
HuRef1660,784,212 - 60,895,817 (+)NCBIHuRef
CHM1_11676,445,151 - 76,557,062 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZNRF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1349961
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.