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Gene: ARR3 (arrestin 3) Homo sapiens
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Symbol: ARR3
Name: arrestin 3
Description: The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: arrestin 3 retinal (X-arrestin); arrestin 3, retinal (X-arrestin); arrestin 4; arrestin-C; ARRX; C-arrestin; cArr; cone arrestin; MYP26; retinal cone arrestin-3; X-arrestin
Orthologs:
Mus musculus (house mouse) : Arr3 (arrestin 3, retinal)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arr3 (arrestin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arr3 (arrestin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ARR3 (arrestin 3)
Canis lupus familiaris (dog) : ARR3 (arrestin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arr3 (arrestin 3)
Sus scrofa (pig) : ARR3 (arrestin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X70,268,335 - 70,281,840 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X69,488,185 - 69,501,691 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,404,910 - 69,418,415 (+)NCBINCBI36hg18NCBI36
Build 34X69,271,222 - 69,284,711NCBI
CeleraX69,841,522 - 69,855,024 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX63,309,253 - 63,322,604 (+)NCBIHuRef
CHM1_1X69,382,163 - 69,395,648 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARR3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350252
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.