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Gene: RUNX1T1 (RUNX1 partner transcriptional co-repressor 1) Homo sapiens
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Symbol: RUNX1T1
Name: RUNX1 partner transcriptional co-repressor 1
CRRD ID: 1350261
Description: Predicted to have identical protein binding activity and transcription corepressor activity. Involved in negative regulation of transcription, DNA-templated. Localizes to nuclear matrix and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acute myelogenous leukemia 1 translocation 1, cyclin-D related; AML1-MTG8; AML1T1; CBFA2T1; CBFA2T1 isoform r1t1-11a61; CBFA2T1 isoform r1t1-11a62; CBFA2T1 isoform r1t1-11a63; CBFA2T1 isoform r1t1-11a64; CBFA2T1 isoform r1t1-11a65; CBFA2T1 isoform r1t1-7a47; CBFA2T1 isoform r1t1-7a48; CBFA2T1 isoform r1t1-7a49; CBFA2T1 isoform r1t1-7a50; CBFA2T1 isoform r1t1-7a51; CBFA2T1 isoform r1t1-7a52; CBFA2T1 isoform r1t1-7d53; CBFA2T1 isoform r1t1-7d54; CBFA2T1 isoform r1t1-7d55; CBFA2T1 isoform r1t1-7d56; CBFA2T1 isoform r1t1-8a57; CBFA2T1 isoform r1t1-8a58; CBFA2T1 isoform r1t1-8a59; CBFA2T1 isoform r1t1-8a60; CDR; core-binding factor, runt domain, alpha subunit 2; core-binding factor, runt domain, alpha subunit 2, translocated to, 1; cyclin D-related; cyclin-D-related protein; DKFZp564B213; eight twenty one protein; ETO; FLJ33145; MGC2796; MTG8; MTG8b; myeloid translocation gene on 8q22; runt related transcription factor 1; runt-related transcription factor 1; RUNX1 translocation partner 1; translocated to, 1; translocated to, 1 (cyclin D related); translocated to, 1 (cyclin D-related); zinc finger MYND domain-containing protein 2; ZMYND2
Orthologs:
Mus musculus (house mouse) : Runx1t1 (RUNX1 translocation partner 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Runx1t1 (RUNX1 partner transcriptional co-repressor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Runx1t1 (RUNX1 partner transcriptional co-repressor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RUNX1T1 (RUNX1 partner transcriptional co-repressor 1)
Canis lupus familiaris (dog) : RUNX1T1 (RUNX1 partner transcriptional co-repressor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Runx1t1 (RUNX1 partner transcriptional co-repressor 1)
Sus scrofa (pig) : RUNX1T1 (RUNX1 partner transcriptional co-repressor 1)
Chlorocebus sabaeus (African green monkey) : RUNX1T1 (RUNX1 partner transcriptional co-repressor 1)
Heterocephalus glaber (naked mole-rat) : Runx1t1 (RUNX1 partner transcriptional co-repressor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl891,954,967 - 92,103,286 (-)EnsemblGRCh38hg38GRCh38
GRCh38891,954,967 - 92,103,451 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37892,967,195 - 93,115,454 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36893,040,328 - 93,176,619 (-)NCBINCBI36hg18NCBI36
Build 34893,040,327 - 93,144,367NCBI
Celera889,157,513 - 89,293,797 (-)NCBI
Cytogenetic Map8q21.3NCBI
HuRef888,174,218 - 88,322,535 (-)NCBIHuRef
CHM1_1893,007,519 - 93,155,728 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RUNX1T1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350261
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.