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Gene: CNKSR2 (connector enhancer of kinase suppressor of Ras 2) Homo sapiens
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Symbol: CNKSR2
Name: connector enhancer of kinase suppressor of Ras 2
Description: This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CNK homolog protein 2; CNK2; connector enhancer of KSR 2; connector enhancer of KSR2; KIAA0902; KSR2; MAGUIN; membrane-associated guanylate kinase-interacting protein; MRXSHG
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X21,374,418 - 21,654,689 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X21,392,532 - 21,672,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X21,302,901 - 21,580,700 (+)NCBINCBI36hg18NCBI36
Build 34X21,152,636 - 21,430,436NCBI
CeleraX25,513,670 - 25,793,712 (+)NCBI
Cytogenetic MapXp22.12NCBI
HuRefX19,116,680 - 19,415,186 (+)NCBIHuRef
CHM1_1X21,422,963 - 21,703,230 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CNKSR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350323
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.