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Gene: CLEC7A (C-type lectin domain containing 7A) Homo sapiens
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Symbol: CLEC7A
Name: C-type lectin domain containing 7A
Description: Exhibits (1->3)-beta-D-glucan binding activity and pattern recognition receptor activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of reactive oxygen species metabolic process; and response to fungus. Localizes to cell surface and cytoplasm. Implicated in aspergillosis and chronic mucocutaneous candidiasis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-glucan receptor; BGR; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; CANDF4; CD369; CLECSF12; DC-associated C-type lectin 1; dectin-1; DECTIN1; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; SCARE2
Orthologs:
Mus musculus (house mouse) : Clec7a (C-type lectin domain family 7, member a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clec7a (C-type lectin domain containing 7A)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLEC7A (C-type lectin domain containing 7A)
Canis lupus familiaris (dog) : CLEC7A (C-type lectin domain containing 7A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clec7a (C-type lectin domain containing 7A)
Sus scrofa (pig) : CLEC7A (C-type lectin domain containing 7A)
Chlorocebus sabaeus (African green monkey) : CLEC7A (C-type lectin domain containing 7A)
Heterocephalus glaber (naked mole-rat) : Clec7a (C-type lectin domain containing 7A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1210,116,777 - 10,130,258 (-)EnsemblGRCh38hg38GRCh38
GRCh381210,116,777 - 10,130,264 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371210,269,376 - 10,282,868 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,160,643 - 10,174,135 (-)NCBINCBI36hg18NCBI36
Build 341210,171,190 - 10,174,103NCBI
Celera1215,430,059 - 15,443,548 (-)NCBI
Cytogenetic Map12p13.2NCBI
HuRef1210,012,523 - 10,026,010 (-)NCBIHuRef
CHM1_11210,238,652 - 10,252,134 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Nomenclature History
 
More on CLEC7A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1350458
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.